Cellular Forté^® with IP-6 and Inositol, is a patented (United States Patent Number 5,082,833) combination of inositol hexaphosphate (IP-6 or phytate) and inositol with a unique 1:1 molecular ratio.¹

HOW DOES IT WORK?
Cellular Forté^® with IP-6 and Inositol provides nutritional support of immune function including healthy cell development and natural killer cell activity.^†

Healthy Cell Development
Healthy cells are characterized by structural and organizational integrity. They have a cytoskeleton composed of bundles of proteins that provide the structure and shape of the cell. Distinct structure and function is an important component in healthy cell development. Healthy cells differentiate from other cells, with disparate and distinct potential for cell development. ^1-3

Healthy cells have cell membranes with complex coverings that determine what molecules can enter and leave the cell. Healthy cell surface function is vital to healthy cell development. A number of biochemical substances are present on cell surfaces and allow healthy cell interaction with other healthy cells. Healthy cells develop from intact and functioning genetic material.^1-3

Natural Killer Cells
Natural killer (NK) cells are a subset of peripheral blood lymphocytes. In contrast to other lymphocytes, NK cells do not require communication with other immune cells prior to activity. NK cells mediate a variety of important healthy immune system functions, including overall surveillance and healthy immunoregulation. Increases in healthy NK cell activity provide support of healthy immune function.^4,5

Inositol Hexaphosphate
Inositol hexaphosphate (IP-6 or phytic acid) is an inositol molecule with six phosphate groups attached. Inositol hexaphosphate is ubiquitous (found everywhere) in the plant kingdom and abundant in cereals and legumes. ^6,7 In smaller amounts, IP-6 is contained in most mammalian cells, where it supports cellular functions.^†8-14 In addition, IP-6 functions as an antioxidant.^†15,16

Inositol
Inositol is a water soluble, ubiquitous 6-carbon sugar. Recognized as part of the vitamin B complex group, inositol is an important dietary and cellular constituent. Major food sources include beans, citrus fruit, nuts, rice, veal, pork, and wheat germ.¹⁷ Inositol supports healthy nerve transmission, healthy fat metabolism, and is needed for cell membrane structure and integrity.^†18-23

Inositol Hexaphosphate and Inositol
While independently these molecules support immune health, the unique combination of IP-6 and inositol functions synergistically.^† Research indicates the combination of IP-6 and inositol supports stronger healthy cell development and increased natural killer cell activity as opposed to either compound alone.^†24-26

Through phosphorylation, inositol molecules can accept up to six phosphate groups. Lower inositol phosphates (IP-1, IP-2, IP-3, and IP-4) act as cellular messengers with varying degrees of activity.²⁷ IP-3, a highly active molecule, has numerous cellular supportive and cellular communication functions.²⁸

Inositol hexaphosphate is hypothesized to support healthy cellular function through dephosphorylation into IP-3.^† When inositol is combined with IP-6, it can accept the phosphates that are liberated from the breakdown of IP-6, thereby increasing the intracellular levels of beneficial IP-3 molecules. ^24-26 Research suggests that IP-6, and its lower phosphorylated, forms help support healthy cell development.^†26-28

Both the molecular ratio and the weight ratio of IP-6 to inositol are important in Cellular Forté^® with IP-6 and Inositol:

One molecule of IP-6 is four times the weight of an inositol molecule. A 1:1 molecular ratio, the ratio that yields maximum IP-3 production, is obtained by combining 400 mg IP-6 to 110 mg of inositol. Any variance from this 1:1 molecular ratio results in a significant reduction of IP-3 molecules produced.¹ It is the molecular ratio, unique to the patent that distinguishes Cellular Forté^® with IP-6 and Inositol from other products. Therefore, no other product can yield the optimal amount of IP-3 that Cellular Forté^® with IP-6 and Inositol can deliver.

RECOMMENDATIONS
Take two Rapid- Release tablets twice daily. Best if taken on an empty stomach. Additional tablets may be taken as needed.

PRECAUTIONS
Inositol hexaphosphate bound to protein in bran or fiber is absorbed more slowly than pure IP-6. Some research has demonstrated that bound IP-6 may interact and potentially bind with minerals in the stomach.10 Because of this potential interaction, it is recommended to take Cellular Forté^® with IP-6 and Inositol on an empty stomach (1/2 hour before or 2 hours after meals).

STORAGE RECOMMENDATIONS
Store at controlled room temperature, 59° to 86°F (15° – 30°C).